Infections

Fighting urinary tract infections with antibiotic and non-antibiotic therapies

Urinary tract infections (UTIs) place a considerable burden on the patient and are associated with substantial economic cost. Treatment of UTIs is mainly achieved using antibiotics, however, the rise in antibiotic resistance is concerning and the use of non-antimicrobial prophylaxis offers alternative treatment methods.

Cranberry derivatives enhance biofilm formation and transiently impair swarming motility of the uropathogen Proteus mirabilis HI4320

Proteus mirabilis is a major cause of catheter-associated urinary tract infection (CAUTI), emphasizing that novel strategies for targeting this bacterium are needed. Potential targets are P. mirabilis surface-associated swarming motility and the propensity of these bacteria to form biofilms that may lead to catheter blockage.

Antibody responses following incident anal and penile infection with human papillomavirus in teenage men who have sex with men

Men who have sex with men (MSM) are at risk for human papillomavirus (HPV) related anal cancer. Few data exist on antibody responses following incident anogenital infection with HPV in teenage MSM. A cohort of 200 MSM aged 16-20 years from Melbourne, Australia were assessed at baseline, 3, 6, and 12 months.

Comparison of the microbiological milieu of patients randomized to either hydrophilic or conventional PVC catheters for clean intermittent catheterization

INTRODUCTION - Control of bacteriuria is problematic in patients who perform clean intermittent catheterization for management of neurogenic bladder. This population is often burdened with multiple urinary tract infections (UTIs), placing them at increased risk of end-stage renal disease.

[Impact of an intervention to improve indwelling urinary catheter use and reduce urinary tract infections]

OBJECTIVE - To evaluate the impact of an intervention regarding the adequate use and improvement in the care of indwelling urinary catheters (IUC) and the frequency of catheter-associated urinary tract infections (CAUTI) in hospitalised patients.

Development and Implementation of a Catheter Associated Urinary Tract Infection (CAUTI) 'Toolkit'

Indwelling urinary catheters are a commonly used invasive medical device within acute and non-acute settings in NHS Scotland. The second National Survey of the Prevalence of Hospital Acquired Infection (HAI) in Scotland 2011 identified that 19.

Cyclic-di-GMP signaling contributes to Pseudomonas aeruginosa mediated catheter-associated urinary tract infection

Bis-(3' -5' ) cyclic dimeric guanosine monophosphate (c-di-GMP) controls the lifestyle transition between the sessile and motile state in many Gram-negative bacteria, including the opportunistic human pathogen Pseudomonas aeruginosa.

Current Concepts in Infections Associated with Penile Prostheses and Artificial Sphincters

Implantation of penile prostheses and artificial urinary sphincters have gained widespread acceptance for the treatment of refractory erectile dysfunction and incontinence, respectively. In the past 3 decades, improved device design and an increased understanding of the pathophysiology of device infections have contributed to a decrease in infection rates.

Urinary Tract Infection and Neurogenic Bladder

Urinary tract infections (UTIs) are frequent, recurrent, and lifelong for patients with neurogenic bladder and present challenges in diagnosis and treatment. Patients often present without classic symptoms of UTI but with abdominal or back pain, increased spasticity, and urinary incontinence.

Using quality improvement methods to prevent catheter-associated UTI

Catheter-associated urinary tract infection (CAUTI) is considered to be reasonably preventable and there is an abundance of published guidance, all of which details similar CAUTI-prevention strategies.

A prospective analysis of urinary tract infections among elderly trauma patients

Catheter-associated urinary tract infections (CAUTIs) have been deemed "reasonably preventable" by the Centers for Medicare and Medicaid, thereby eliminating reimbursement. Elderly trauma patients, however, are at high risk for developing urinary tract infections (UTIs) given their extensive comorbidities, immobilization, and environmental changes in the urine, which provide the ideal environment for bacterial overgrowth.

Dalfampridine does not increase the risk of urinary tract infections in patients with multiple sclerosis - Beyond the Abstract

The process of normal micturition is dependent on neural integration between the central and peripheral nervous systems. In diseases such as multiple sclerosis (MS), impaired neural integration may lead to neurogenic bladder and lower urinary tract dysfunction.  Bladder symptoms and the need for catheterization in some patients increase the risk for urinary retention and urinary tract infection (UTI). 

Evaluation of efficacy and tolerability of cefotaxime and sulbactam versus cefepime and tazobactam in patients of urinary tract infection-a prospective comparative study - Beyond the Abstract

Treating urinary tract infection is still a major health challenge in developing countries. Cephalosporins are one of the mainstays of therapy and third generation among these are the first line agents for treatment of complicated UTIs including those of nosocomial origin.

Ultrasonography findings and blood CRP levels can predict the outcomes of VCG after the first UTI in children - Beyond the Abstract

Urinary tract infection (UTI) is one of the most frequent bacterial infections in children together with bacterial respiratory infections. Underlying diseases such as vesicoureteric reflux (VUR) also arise in some patients with UTI.

Impact of an antimicrobial stewardship intervention on urinary tract infection treatment in the ED - Abstract

STUDY OBJECTIVE: The study objective is to assess changes in treatment of uncomplicated urinary tract infections (UTIs) after implementation of recommendations based on national guidelines and local resistance rates.

Frequency of occurrence of urinary tract infection in double J stented versus non-stented renal transplant recipients - Abstract

Prophylactic ureteric stenting in renal transplant recipients prevents major surgical complications such as ureteric leak and obstruction on the one hand while, on the other hand, it is associated with complications like urinary tract infections (UTI), hematuria, stent migration, stent encrustation and forgotten stents.

Urinary tract infection following posterior lumbar fusion procedures: An ACS-NSQIP Study - Abstract

STUDY DESIGN: Retrospective review of prospectively collected data.

Emergence of Raoultella ornithinolytica on O'ahu: A case of community-acquired R. ornithinolytica urinary tract infection - Abstract

Human infection with Raoultella ornithinolytica is rare, with only ten cases having been reported previously.

Significance of procalcitonin measurement in cases with febrile condition during chemotherapy for urological cancer - Abstract

We examined the usefulness of measurement of procalcitonin (PCT) for patients, who developed febrile neutropenia during cancer chemotherapy for urological cancer.

Diagnostic accuracy of the urinalysis for urinary tract infection in infants less than 3 months of age - Abstract

BACKGROUND: The 2011 American Academy of Pediatrics urinary tract infection (UTI) guideline suggests incorporation of a positive urinalysis (UA) into the definition of UTI.