Department of Urology, Skåne University Hospital, University of Lund, S-20502 Malmö, Sweden.
Surgical site infections (SSI) including urinary tract infections (UTI) cause a significant morbidity in urological surgery. Antibiotic prophylaxis is one of several factors impacting on infection rates. Antibiotic prophylaxis is relevant only for clean and clean-contaminated operations and in the absence of bacterial growth in the urine. Strict classification of urological procedures is lacking, but a proposal is presented elsewhere. Only TURP and transrectal core prostate biopsy are well documented. The present review confirms that there is a lack of hard data, insufficient consistency in classification and definitions, and that new well-powered RCT and large multicentre quality cohort studies including risk factor analysis are necessary to improve recommendations for antibiotic prophylaxis in urologic surgery.
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Reference: Int J Antimicrob Agents. 2011 Oct 11. Epub ahead of print.
doi: 10.1016/j.ijantimicag.2011.09.008
PubMed Abstract
PMID: 21996404
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