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Consensus update on the therapeutic approach to patients with neurogenic detrusor overactivity

Introduction and objectives: A Consensus document on the management of patients with neurogenic detrusor overactivity (NDO) was published in 2018. The present document aims to update its recommendations regarding treatment considering the new evidence available, and to contribute to the standardization of the management of this disorder.

Methods: The methodology used was based on a systematic review and the Nominal Group Technique. The clinical coordinator (CC) and the Consensus update group (CUG) defined the questions to be updated and carried out a systematic review to identify the new available evidence. After being evaluated by the expert panel, the relevant recommendations were updated and agreed in a consensus meeting.

Results: A total of 3210 publications were identified and 26 publications that met the inclusion criteria were included. The CUG updated 18 recommendations on the therapeutic approach to NDO. Unanimous consensus was reached on all of them.

Conclusions: Previous recommendations need to be revised due to the availability of new drugs, the increasing evidence on the use of botulinum toxin or neuromodulation procedures, and new surgical options.

A Borau,1 J Salinas,2 M Allué,3 D Castro-Diaz,4 M Esteban,5 S Arlandis,6 M Virseda,7 J M Adot8

  1. Insituto Guttmann, Barcelona, Spain. Electronic address: .
  2. Hospital Clínico San Carlos, Madrid, Spain.
  3. Hospital Universitario Vall d´Hebron, Barcelona, Spain.
  4. Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain.
  5. Hospital Nacional de Parapléjicos, Toledo, Spain.
  6. Hospital Universitario y Politécnico La Fe, Valencia, Spain.
  7. Hospital Clinico San Carlos, Madrid, Spain.
  8. Hospital General Universitario, Burgos, Spain.

Source: A Borau, J Salinas, M Allué et al. Consensus update on the therapeutic approach to patients with neurogenic detrusor overactivity. Actas Urol Esp (Engl Ed). 2024 May 14:S2173-5786(24)00073-8. doi: 10.1016/j.acuroe.2024.05.013.

Neurogenic Bladder Foundations