Advanced Prostate Cancer COE

The Best Use of Antiresorptive Therapy in CRPC Presentation - Matthew Smith

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Matthew Smith presented a summary detailing the best use of osteoclast-targeted therapy for patients with bone metastatic castration-resistant prostate cancer (mCRPC) at the Advanced Prostate Cancer Consensus Conference (APCCC) 2019. Emphasizing the importance to distinguish between skeletal-related events and fragility fractures secondary to osteoporosis, Dr. Smith covers the current landscape fo...

The Management of Fatigue, Cognition, and Dementia in Prostate Cancer Patients Presentation - Charles Ryan

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Charles Ryan presented the management of fatigue and cognitive changes induced by androgen deprivation therapy (ADT) at the Advanced Prostate Cancer Consensus Conference (APCCC 2019). Dr. Ryan discusses the association between ADT and dementia, and also how combining ADT with abiraterone and prednisone can significantly improve fatigue in patients. Biographies: Charles J. Ryan, MD , the President...

Management of ADT Metabolic Complications: Assessment, Monitoring, Interventions Presentation - Neal Shore

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Neal Shore presents on the metabolic complications of androgen deprivation therapy and how to manage them at the Advanced Prostate Cancer Consensus Conference (APCCC 2019). Biography: Neal Shore, MD , Medical Director for the Carolina Urologic Research Center, Myrtle Beach, South Carolina, USA. Related Content: APCCC 2019: Management of Metabolic Changes Download Presentation Slides Read the Full...

The Future of Advanced Prostate Cancer Management: Access to Treatments Presentation - Karim Fizazi

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Karim Fizazi presented on global access to treatment of advanced prostate cancer at the Advanced Prostate Cancer Consensus Conference (APCCC 2019). He includes data on current access to radiotherapy on a worldwide level, the use of generic drugs, including docetaxel, abiraterone, and cabazitaxel expected to start in 2021. Lastly, he highlights the use of surgical castration vs. the use of LHRH ago...

The Future of APC Management in Polymetastatic Disease Presentation - William Oh

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In the last 10 years, there has been tremendous progress in the available treatment options for metastatic prostate cancer patients. In this presentation from William Oh at the 2019 Advanced Prostate Cancer Consensus Conference he highlights available treatment options for metastatic prostate cancer patients including serial systemic therapy with combinations of ADT with chemotherapy, abiraterone,...

Which Systemic Therapy for Which Patient with Newly Diagnosed Metastatic Prostate Cancer Presentation - Chris Sweeney

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Christopher Sweeney presents on systemic therapy for prostate cancer at the Advanced Prostate Cancer Consensus Conference (APCCC 2019). The spectrum of patients starting androgen deprivation therapy (ADT) for metastatic disease is quite vast. Discussing several treatments and several studies as well as their overall survival treatment benefit Dr. Sweeney focuses on which systemic therapy for which...

Clinical Trial Treatment Options for Rare GU Malignancies - Bradley McGregor

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Alicia Morgans and Brad McGregor discuss rare genitourinary histologies and the efforts to find treatment options for populations not always included in clinical trials. Most clinical trials are developed and designed for the most common subtypes, not including atypical variant histologies often found in bladder and prostate cancers. Given the tumor agnostic approach of immunotherapy, Brad and his...

Sinai Researchers Find First Mechanistic Link between World Trade Center Dust & Prostate Cancer - William Oh

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William Oh highlights the first study of people who were exposed to the World Trade Center dust and who subsequently developed prostate cancer. World Trade Center responders with prostate cancer showed signs that inflammation was activated in the prostate after exposure to dust from the World Trade Center site, possibly causing chronic inflammation that contributed to their cancer, according to a...

APCCC 2019 Global vs. Expert Consensus in the Management of Advanced Prostate Cancer Study - Charles Ryan

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Charles Ryan and Alicia Morgans encourage participation in a 6 minute (survey) study available on UroToday.com, titled the Global vs. Expert Consensus in the Management of Advanced Prostate Cancer Study , a questionnaire intended to determine the global consensus among all physicians treating patients with advanced prostate cancer. The aim is to further understand global patterns of care in advanc...

Baseline PSA Level in Midlife and Aggressive Prostate Cancer in African American Men - Mark Preston

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Alicia Morgans and Mark Preston share a discussion on his recent paper Baseline Prostate-specific Antigen Level in Midlife and Aggressive Prostate Cancer in Black Men published in European Urology which set to determine whether baseline PSA level during midlife predicts the risk of aggressive prostate cancer in African American men. They also discuss whether the baseline PSAs could correlate with...