Advanced Kidney Cancer COE - Results from #100

Advanced Kidney Cancer COE

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CABOSUN Trial Plus an In-depth Discussion of Kidney Cancer Treatments - Toni Choueiri Details (Length of Discussion: 22 min) Alicia Morgans and Toni Choueiri engage in a discussion on the treatment options available for mRCC. Toni presents a thorough review of the CABOSUN results, further addressing the process of choosing the right first-line therapy for these patients with intermediate, and poor risk disease. His extensive work in research provides an optimistic vision of having a biomar...
CARMENA: Practice Changing Strategies for Kidney Cancer Details (Length of Discussion: 6 min) Charles Ryan and Dan George reflect on the dramatic changes clinicians have seen over the last 12 years in treating kidney cancer. Dan reviews the highlights of the CARMENA trial and the impact that the results have made to treatment strategies for patients, stressing the value of collaborative care and patient selection. Biographies: Daniel George, MD Charles J. Ryan...
Discussion of the IMmotion 151 Trial: Atezolizumab Plus Bevacizumab vs Sunitinib in Untreated Metastatic Renal Cell Carcinoma - Thomas Keane Details (Length of Discussion: 5 min) Dr. Thomas Keane reviews the IMmotion 151 Trial, a randomized Phase III Study of Atezolizumab Plus Bevacizumab versus Sunitinib in Untreated Metastatic Renal Cell Carcinoma. A topic presented by Robert J. Motzer, MD at the 2018 ASCO GU 2018 meeting. In this oral abstract session, Dr. Motzer presented the first phase III randomized clinical trial combining a PD-L1/PD-1...
Discussion of the CABOSUN trial - Advanced Renal Cell Carcinoma - Thomas Keane Details (Length of Discussion: 4 min) Dr. Thomas Keane reviews the Subgroup Analysis of Progression-free Survival and Objective Response Rate in the Alliance AO31203 CABOSUN trial for Advanced Renal Carcinoma presentation by Dr. Daniel George at the ASCO GU 2018 meeting. Cabozantinib, a small molecule designed to target the MET and ALK pathways in addition to VEGFR2 pathway has been shown to be superior t...