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- Joining Alicia Morgans to discuss a plenary abstract presentation from the 2021 American Society of Clinical Oncology Genitourinary Cancers Symposium (ASCO GU) is Atish D. Choudhury, MD, Ph.D. Dr. Choudhury and colleagues presented the results of a phase II study to assess the safety of the combination and differences in immune cell infiltrate in bone biopsies (bx) and preliminary clinical activit...
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- Oliver Sartor, MD joins Alicia Morgans, MD, MPH to discuss a real-world clinical outcomes study of sequential novel antihormonal therapy (abiraterone or enzalutamide) or radium-223 (Ra-223) treatment of metastatic castration-resistant prostate cancer (mCRPC) that progressed after first-line NAH. This data is taken from the real world reports in the Flatiron Registry. Dr. Sartor presented this data...
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- Matthew Smith shares his thoughts on the importance of bone health in the prostate cancer patient population. Osteoporotic or fragility fractures are common due to the age of the patient and long-term androgen deprivation therapy. Fractures have a great impact on patient mortality, mobility, independence, and overall quality of life. Dr. Smith addresses questions regarding bone density measurement...
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- Hossein Jadvar presents on the use of sodium fluoride and radium-223 as a theranostic pair in the treatment of patients with metastatic prostate cancer. 18 F-sodium fluoride has experienced a remarkable recent renaissance in the management of neuroendocrine tumors and prostate cancer. Dr. Jadvar presents this information during the annual meeting of the Society of Nuclear Medicine and Molecular Im...
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- Neal Shore joins Alicia Morgans in a discussion on the optimal timing to use radium-223 (Xofigo®) in metastatic castration-resistant prostate cancer (mCRPC). Together they discuss the window of opportunity for administering radium-223 and what we have learned from the ALSYMPCA and ERA-223 trials. Dr. Shore recaps how radium-223 is being used prior to docetaxel and how it is being layered with an a...
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- Hossein Jadvar joins Phillip Koo for the last in its series of video presentations in the Society of Nuclear Medicine SNMMI video lecture series. Dr. Jadvar presents on the topic of Radium 223 dichloride use in patients with castrate-resistant prostate cancer. (Length of Interview: 34 min) Biographies: Phillip J. Koo, MD is the Division Chief of Diagnostic Imaging at the Banner MD Anderson Cancer...
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- Alicia Morgans and Fred Saad have a discussion on bone health in prostate cancer patients, an issue for men with advanced prostate cancer and an important topic to keep at the forefront of care. Even though men are living longer, bone metastases increases mortality and impair a person's independence. Fred and Alicia tackle approaching this in your patients, specifically in the metastatic castratio...
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- Oliver Sartor presented the impact and use of radium-223 during the Bone and Bone Metastases Session at the Advanced Prostate Cancer Consensus Conference (APCCC 2019). Dr. Sartor explains how Radium-223 first gained prominence with the reporting of the ALSYMPCA trial in 2013 which led to the FDA approval of radium-223 in the United States for patients with bone mCRPC without visceral metastases hi...
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- Bertrand Tombal presented the use of antiresorptive therapy to reduce the risk of skeletal-related events (SRE) for the majority of men with castration-resistant prostate cancer (CRPC) and bone metastases. This presentation was part of the debate regarding how aggressive to be with bone-targeted therapy at the Advanced Prostate Cancer Consensus Conference (APCCC) 2019 biennial meeting. Dr. Tombal'...
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- Phillip Koo joins Neal Shore to discuss radium 223 for treating men with metastatic castration-resistant prostate cancer. Radium-223 has improved overall survival (OS) and reduced symptomatic skeletal events (SSE) in patients with metastatic castration-resistant prostate cancer (mCRPC) and bone metastases (ALSYMPCA trial). The survival benefit and the safety and tolerability profile of radium-223...
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