BACKGROUND: Catheter-associated urinary tract infection (CAUTI) is a common clinic problem.
The purpose of this study was to investigate recent trends in CAUTI in neurogenic bladder patients focusing on extended-spectrum β-lactamase (ESBL)-producing Escherichia coli.
METHODS: Isolates from the urine of neurogenic bladder patients with UTI were investigated. Nine strains of ESBL-producing E coli were assayed by molecular strain typing using the Diversilab system for repetitive-sequence-based polymerase chain reaction (rep-PCR).
RESULTS: E coli accounted for most of the bacteria (74.1% to 81.0%) that produced ESBLs. Rep-PCR data showed that 7 out of 9 ESBL-producing E coli belonged to the same typing group with high similarity (more than 97% similarity) and that this distribution corresponded with antibiotic resistance patterns.
CONCLUSION: ESBL producing E coli strains isolated from CAUTI patients could be discriminated by rep-PCR typing using the Diversilab system in consistent with antibiotic resistance patterns.
Written by:
Takaba K, Shigemura K, Osawa K, Nomi M, Fujisawa M, Arakawa S. Are you the author?
Department of Clinical Laboratory, Hyogo Prefectural Rehabilitation Center, Kobe, Japan; Division of Urology, Department of Surgery Related, Kobe University Graduate School of Medicine, Kobe, Japan; Infection Control Team, Kobe University Hospital, Kobe, Japan; Infection Control Team, Kobe University Hospital, Kobe, Japan; Department of Urology, Hyogo Prefectural Rehabilitation Hospital, Kobe, Japan.
Reference: Am J Infect Control. 2014 Mar;42(3):e29-31.
doi: 10.1016/j.ajic.2013.11.018
PubMed Abstract
PMID: 24581025
