EAU 2019: Immediate Preoperative Blood Glucose and Hemoglobin A1c Levels are Not Predictive of Post-operative Infections in Diabetic Men undergoing Penile Prosthesis Placement

Barcelona, Spain (UroToday.com) It was previously claimed that pre-operative blood glucose levels could be a predictive factor for infection rates in patients undergoing penile prosthesis (PP) implantation. However, the authors of this multi-institutional study sought to assess the veracity of these reports.

A retrospective review of 669 diabetic patients from April 2003 to May 2018 was performed, assessing pre-operative serum blood glucose (PBG) and HbA1c levels in patients that underwent primary PP placement. Other covariates such as age, diabetes type, diabetes-related complications, BMI, prosthesis type, Charlson Comorbidity Index, history of immunosuppression and prior radical prostatectomy were evaluated as well. All variables were assessed for correlation to post-operative infection, revision, and explantation rates.

Despite previous suggestions, they found that preoperative blood glucose and HbA1c levels were not predictive of postoperative infection, revision, or explanation rates. Additionally, no significant predictors were found in multivariate analysis in predicting risks of explantation and revision. However, they did find that after controlling for preoperative HbA1c, PBG, and age, patients with a prior history of DM-related complications had an increased risk of postoperative infection by about 3.2 times.

Presented by: Linda My Huynh, Senior Clinical Research Coordinator, Department of Urology, University of California-Irvine

Written by: Kaelyn See, Department of Urology, University of California-Irvine, at the 34th European Association of Urology (EAU 2019) #EAU19 conference in Barcelona Spain, March 15-19, 2019.