SUFU 2020: Audio-Visual Stimuli in an Oral Hydration Study: Heightened Response in Overactive Bladder Participants

Scottsdale, AZ (UroToday.com) Kaitlyn Maddra presents their research on audio-visual stimulation triggering urgency in overactive bladder patients. They aimed to quantify the changes in sensation with a non-invasive hydration study. They grouped healthy and OAB patients based on ICIq-OAB survey. A 6 question survey on triggers was provided.

SUFU 2020 AV OAB table 1 trigger survey

The study participants were given an oral hydration protocol (3 Fill). They drank 2 liters of Gatorade G2 during fill 1 and water during fills 2 and 3. A tablet-based meter was used to measure bladder sensation from 0-100%. At 50% sensation, a 3-minute video was watched showing different scenes with water.

SUFU 2020 AV OAB 3 fill

The change in sensation was calculated and the results are in the table below.

SUFU 2020 AV OAB table 2 sensation

Kaitlyn concludes that there is a correlation between running water with trigger survey.

SUFU 2020 AV OAB table 3 correlation

A non-invasive hydration protocol can help in identifying environmental triggers, but more research is needed.

There was a suggestion from the audience to have patients bring images of own bathroom. Previous research has been done with the patient's own bathroom photo and looking at fMRI had higher activation patterns of bladder fullness.


Presented by: Kaitlyn Maddra, Virginia Commonwealth University School of Medicine, Richmond, Virginia

Co-Authors: Urmila Sivagnanalingam1, Natalie Swavely, MD2, Priscilla Koirala1, Kaitlyn Maddra1, Rui Li, PhD3, Kyla Egenberger3, Sydney Roberts3, Samuel Weprin, MD2, Adam Klausner, MD2, John Speich, PhD3

1. Virginia Commonwealth University School of Medicine. Richmond, Virginia
2. Virginia Commonwealth University, Department of Surgery, Division of Urology, Richmond, Virginia
3. Virginia Commonwealth University College of Engineering, Department of Mechanical Nuclear Engineering, Richmond, Virginia

Written by: Lira Chowdhury, DO, Urology Specialist, Urology Partners of North Texas, PLLC, Fort Worth, Texas at the Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction Winter Meeting, SUFU 2020, February 25 - February 29, 2020, Scottsdale, Arizona