SUFU 2021: The Prevalence of Antimicrobial Resistant Pathogens Causing Recurrent Urinary Tract Infections Amongst Female Patients in an Outpatient Female Pelvic Medicine Practice in the NY/NJ Metropolitan Area
Antimicrobial resistance (AMR) patterns among the uropathogens were compared between the two groups of women. 334 patients were identified with UTIs and 704 positive cultures. 46.4% of patients were classified as rUTI. Compared to patients with sUTI, rUTI represented an older population among the rUTI's, 54 % were >70 years old vs 38% sUTI (p= 0.006). The most common uropathogens were E. coli and K. pneumonia accounting for 58% and 19% of all organisms, respectively. In patients with rUTI, 34% of E. coli were resistant to 3 or more oral antibiotics compared to 20% among cultures from sUTI patients (p=0.003). Resistance to fluoroquinolones and trimethoprim-sulfamethoxazole were more common among E. coli isolates recovered from rUTI patients compared to sUTI patients (40% rUTI vs 28% sUTI). Almost half of this patient population had rUTI. These findings support recent guidelines advocating for routine microbiologic assessment including drug susceptibility to inform effective therapy in patients with rUTI.
Presented by: Marcus Cunningham, Barry N. Kreiswirth, Claudia Manca, Barun Mathema, Jared Benjamin, Deborah Fromer Center for Discovery and Innovation, Nutley, NJ, Department of Urology, Hackensack University Medical Center
Written by: Diane K. Newman, DNP, CRNP, FAAN, BCB-PMD, Nurse Practioner and Co-Director, Penn Center for Continence and Pelvic Health Adjunct Professor of Urology in Surgery during the 2021 Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction (SUFU) Winter Meeting.