In his study, they recruited 54 patients who underwent RIRS that were randomized into either 9.5 Fr UAS or a 12 Fr UAS. For these patients, urine samples were taken right before the procedure, 2 hours after and 24 hours after the procedure. With these samples, the researchers measured the various kidney injury markers aforementioned. Regarding their demographic data, the results were similar between group 1 and 2 (Table below). And, regarding the basal levels of the urine biomarkers, only KIM-1 was higher in group 2 with the others being similar in both groups.
When looking at urinary biomarkers alterations, there was no significant difference in group 1; but in group 2, all urinary biomarkers were significantly increased postoperatively after the procedure. (table below)
Dr. Tuncel concluded that from their study the kidney biomarkers were increased 2 hours after the procedure for patients who received thicker sized UAS. From these results, he recommended that thin UAS be preferred over thick UAS. A member of the audience began to argue against UAS, in general, saying that sometimes procedures may be done even without thin UAS and complications can be prevented altogether.
Presented by: Altug Tuncel, MD, University of Health Sciences, Ankara Numune Research and Training Center
Authors: Can Aykanat, Melih Balci, Kilinckaya Muhammed, Seref Coser, Ali Ozercan, Serkan Akdemir, Ozer Guzel, Murat Arslan, Turan Turhan, Yilmaz Aslan
Affiliation: University of Health Sciences, Ankara Numune Research and Training Center
Written by: John Sung, @JohnM_Sung, Department of Urology, University of California-Irvine, medical writer for UroToday.com at the 36th World Congress of Endourology (WCE) and SWL - September 20-23, 2018 Paris, France