WCE 2017: Systematic Biomineralization in Kidney Stone Formers
The study consisted of a retrospective review of clinical, non-contrast CT scans of abdomen/pelvis in SFs and were compared to CT scans of age and gender matched NSFs (renal transplant donors) as a control. Calcifications were identified in 9 non-renal anatomical locations and were graded based on calculated CT volume.
The resulting data showed a significantly higher average total systematic biomeralization scores in the SFs than the controls, with higher average mineralization scores for the SFs in all 9 individual anatomical locations. These findings may give urologists an opportunity to determine whether patients may be at a higher risk of developing future adverse cardiac and vascular events.
In closing, Dr. Tzou mentioned that non-renal, non-osseous sites of mineralization is not well understood. He hopes that this work will lead to a better understanding of the underlying mechanisms of kidney stone formation. Dr. Tzou also hinted at the possibility of using a computer program that would be able to recognize non-renal mineralizations from CT images, thus predicting whether or not a patient is at risk of having kidney stones in the future.
Presented by: David T. Tzou, MD
Authors: Benjamin A. Sherer, Adrian Fernandez, David T. Tzou, Sunita P. Ho, Marshall L. Stoller
Affiliation: Department of Urology - University of California, San Francisco
Written by: Zachary Valley, Department of Urology, University of California-Irvine at 35th World Congress of Endourology– September 12-16, 2017, Vancouver, Canada.