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EXPERT-LED JOURNAL CLUB DISCUSSIONS
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Comparative Analysis of Radical Cystectomy and Trimodality Therapy for Muscle-Invasive Bladder Cancer - Journal Club
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Rashid Sayyid, MD, MS and Zachary Klaassen, MD, MSc
Rashid Sayyid and Zach Klaassen discuss a study published in Lancet Oncology titled, “Radical Cystectomy versus Trimodality Therapy for Muscle-Invasive Bladder Cancer: A Multi-Institutional Propensity Score Matched and Weighted Analysis.”
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| Two-Year Follow-Up: Avelumab Improves Survival in Advanced Urothelial Carcinoma - Journal Club
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| Rashid Sayyid, MD, MS and Zachary Klaassen, MD, MSc
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| In this discussion between Rashid Sayyid and Zach Klaassen, the experts review the outcomes of the JAVELIN Bladder 100 trial. The trial investigated the effects of Avelumab, a first-line maintenance therapy for advanced urothelial carcinoma and involved 700 patients who showed no disease progression after first-line chemotherapy.
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| Ga-PSMA PET for Evaluation of Response to Chemotherapy for Metastatic Prostate Cancer - Journal Club
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| Rashid Sayyid, MD, MS and Zachary Klaassen, MD, MSc
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| Rashid Sayyid and Zach Klaassen analyze a study on the prognostic role of 68Ga-PSMA-11 PET-based response in prostate cancer patients undergoing taxane-based chemotherapy. The study aimed to compare traditional criteria with newer frameworks incorporating PSMA-PET/CT based criteria, such as PERCIST and PSMA PET Progression.
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| Evaluating Outcomes of Enzalutamide and Abiraterone Co-administration: Insights from the ALLIANCE Trial - Journal Club
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| Rashid Sayyid, MD, MS and Zachary Klaassen, MD, MSc
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| Rashid Sayyid and Zach Klaassen discuss a study on the efficacy of combining enzalutamide and abiraterone in treating metastatic castration-resistant prostate cancer (mCRPC) patients. The study, published in the Journal of Clinical Oncology, posits the potential benefit of using both drugs as they counteract each other's resistance mechanisms.
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