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PEER-TO-PEER CLINICAL CONVERSATIONS
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Occupational and Environmental Factors Linked to Bladder Cancer in High-Risk Groups
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| Sunil Patel, MD, MA |
| Ashish Kamat speaks with Sunil Patel about a BCAN Think Tank breakout session focused on occupational and environmental risk factors in bladder cancer prevention. The discussion explores the impact of exposure to burn pits among military veterans and environmental hazards faced by firefighters, highlighting the complex mixture of potential carcinogens including polycyclic aromatic hydrocarbons, heavy metals, and other toxic compounds. |
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| Clearing the Smoke: Underreporting of Smoking Status in Bladder Cancer Clinical Trials |
Hannah Kay, MD, and Marc Bjurlin, DO, MSC, FACOS
Ruchika Talwar hosts Hannah Kay and Marc Bjurlin to unravel their study on the sparse reporting of smoking status in bladder cancer trials. Their research, "Clearing the Smoke," highlights a concerning discrepancy: only 41.2% of bladder cancer trials over the past decade reported participants' smoking status, starkly contrasting with higher reporting rates in lung cancer trials. |
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Working Group Addresses Excellence in Community Bladder Cancer Care Delivery
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Janet Kukreja, MD
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| Ashish Kamat speaks with Janet Kukreja about a working group session at the BCAN Think Tank, focusing on establishing excellence in community-based bladder cancer care. The discussion explores findings from a collaboration between BCAN and the Association of Cancer Care Centers, highlighting challenges faced by community practices in delivering comprehensive bladder cancer treatment.
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| Exposures and Bladder Cancer Risk Among Military Veterans: A Systemic Review and Meta-Analysis
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| Gal Saffati, MD
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| Gal Saffati presented a systematic review and meta-analysis showing a significant association between military exposures to Agent Orange and depleted uranium and an increased risk of bladder cancer among veterans. The study, which reviewed 26 studies including over 4 million patients, highlighted the need for early screening and preventive strategies for veterans exposed to these agents.
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| Implementation of Smoking Cessation for Patients with Bladder Cancer |
| Marc Bjurlin, DO, MSc |
| Marc Bjurlin highlights the critical role of smoking cessation in improving outcomes for bladder cancer patients, noting that smoking is a primary risk factor for bladder cancer and contributes to recurrence, progression, and mortality. Despite its importance, smoking cessation is infrequently discussed by urologists, often due to time constraints, perceived lack of efficacy, or lack of training. |
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| Identifying Individual and Community-Level Drivers of Disparities in Bladder Cancer Clinical Trials Participation |
| Rishi Sekar, MD |
| Rishi Sekar presents the findings on the impact of individual and community-level factors on disparities in bladder cancer clinical trial participation. His research highlighted that socially vulnerable patients, particularly those in areas with higher Social Vulnerability Index scores, are less likely to be aware of, discuss, or participate in clinical trials, despite having higher cancer mortality rates. |
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Impact of Agent Orange Exposure on Non-Muscle Invasive Bladder Cancer Outcomes - Beyond the Abstract
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| Kyle Richards, MD, FACS |
| In a study on the impact of Agent Orange exposure on non-muscle invasive bladder cancer (NMIBC) outcomes, Dr. Kyle Richards and colleagues utilized Veterans Affairs databases to assess whether Agent Orange exposure affected cancer prognosis in veterans. They found no significant difference in NMIBC outcomes between those exposed to Agent Orange and those not exposed, which is reassuring for patients and healthcare providers. |
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| The Potential Role of Urinary Microbiota in Bladder Carcinogenesis: A Systematic Review - Beyond the Abstract |
| Sakineh Hajebrahimi, MD |
| Sakineh Hajebrahimi’s systematic review on the urinary microbiota's potential role in bladder carcinogenesis explores whether microbial imbalances in the urinary tract might contribute to bladder cancer development and progression. Findings showed notable variations in the urinary microbiota composition between BC patients and healthy individuals, as well as differences between non-muscle invasive and muscle invasive bladder cancer types. |
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