Uroalerts Men's Health Weekly

January 20, 2025

Videos

Peer-to-Peer Clinical Conversations

Incorporating New Approaches for Evaluating, Diagnosing, and Treating BPH "Presentation" - Kevin McVary, Timothy McClure & Kevin Zorn

Kevin T. McVary

At the 2024 LUGPA annual meeting, Kevin McVary, Timothy McClure, and Kevin Zorn explore BPH management through case scenarios, examining medical therapy, minimally invasive techniques, and PAE's role.

Review of Medical Therapy Options in Updated AUA Guidelines for BPH Management, Journal Club - Rashid Sayyid & Zachary Klaassen

Zachary Klaassen

Rashid Sayyid and Zach Klaassen discuss the AUA's updated guidelines for managing lower urinary tract symptoms due to BPH, with a focus on medical therapy.

Beyond the Abstracts

The Impact of Testosterone Therapy on Benign Prostatic Hyperplasia in Hypogonadal Men - Beyond the Abstract

Evaluation of the Learning Curve for Thulium Fiber Laser Enucleation of Prostate (ThuFLEP): Retrospective Study of a Single-Surgeon Experience in Real-World Settings - Beyond the Abstract

Conference Coverage

SUO 2024: Adjuvant Chemotherapy after Primary RPLND for Seminoma - When, Who, if Ever?

WCET 2024: The Prostate Microbiome is Associated with Prostate Size in BPH Patients

ASCO 2024: HERCULES (LACOG 0218): A Phase II Trial of Pembrolizumab plus Platinum-Based Chemotherapy as First-Line Systemic Therapy in Advanced Penile Cancer

Articles

Editor Selected Abstracts and Commentaries

Male Infertility

Does age matter? Impact of age on testicular function and pregnancy outcomes following microsurgical varicocelectomy in patients with grade 3 varicocele.

Novel biallelic MCMDC2 variants were associated with meiotic arrest and nonobstructive azoospermia.

A recurrent loss-of-function variant in DRC1 causes non-syndromic severe asthenozoospermia with favorable intracytoplasmic sperm injection and pregnancy outcomes.

Testicular mapping-guided sperm retrieval vs. upfront microTESE in non-obstructive azoospermia: a comparison of sperm retrieval, pregnancy and live-birth rates.

Peyronie's Disease

Effects of therapy in experimental models of Peyronie's disease: a scoping review.

Prostatitis

The "prostate-pelvic syndrome" theory used in patients with type-III prostatitis and its correlation with prostate volume.

Erectile Dysfunction

Histone deacetylase 6 inhibition prevents hypercholesterolemia-induced erectile dysfunction independent of changes in markers of autophagy.

Prevalence and quality of life associated with erectile dysfunction and lower urinary tract symptoms: a cross-sectional study.

Association of total testosterone levels with cardiometabolic diseases in men with erectile dysfunction.

BPH - Benign Prostatic Enlargement

Benign Prostatic Hyperplasia Knowledge Deficits Among Male Urology Patients.

Relative fat mass is a valuable predictor of lower urinary tract symptoms suggestive of benign prostatic hyperplasia in aging males: clinical implications.

The impact of kidney disease on peri-operative outcomes of novel BPH surgeries across the board: a propensity score matched analysis using the ACS-NSQIP database.

The predictive value of prostate spherical volume ratio in lower urinary tract symptoms and clinical progression of benign prostatic hyperplasia: a retrospective cohort study.

Asthma-associated prostate enlargement and bladder smooth muscle hypercontractility: unveiling a potential link to LUTS.

The Impact of Testosterone Therapy on Benign Prostatic Hyperplasia in Hypogonadal Men - Beyond the Abstract

Penile & Urethral Cancers

Organ-sparing partial glansectomy: an alternative surgical management for invasive penile carcinoma-case report.

Tumor-infiltrating plasma cells are a prognostic factor in penile squamous cell carcinoma.

Real-World Outcomes in Patients with Advanced Penile Squamous Cell Carcinoma Receiving Immune Checkpoint Inhibitors: A Single Institution Experience.

Testicular Cancer

Smoking and testicular cancer: A Danish nationwide cohort study.

Networks of pre-diagnostic circulating RNA in testicular germ cell tumour.

The Outcomes of Onco-Testis Sperm Extraction at the Time of Radical Orchiectomy.

Oncological Outcomes Following Robotic Postchemotherapy Retroperitoneal Lymph Node Dissection for Testicular Cancer: A Worldwide Multicenter Study - Beyond the Abstract

Late Side Effects of Testicular Cancer and Treatment: A Comprehensive Review - Beyond the Abstract

Prostate Cancer

Perspectives of clinicians and screening candidates on shared decision-making in prostate cancer screening with the prostate-specific antigen (PSA) test: a qualitative study (PROSHADE study).

Pelvic Lymph Node Dissection in Prostate Cancer: Update from a Randomized Clinical Trial of Limited Versus Extended Dissection - Beyond the Abstract

Evaluating the feasibility of AI-predicted bpMRI image features for predicting prostate cancer aggressiveness: a multi-center study.

Current insights on PSMA PET/CT in intermediate-risk prostate cancer: a literature review.

Prospective validation study of a combined urine and plasma test for predicting high-grade prostate cancer in biopsy naïve men.

Impact of Additional Active Treatment for Prostate Cancer on Health-related Quality of Life of Men: Results from the EUPROMS 2.0 1-year Follow-up Survey.

Screening for Predictive Factors of Efficacy of Second-Generation Androgen Receptor Axis-Targeted Agents in Patients With High-Risk Metastatic Hormone-Sensitive Prostate Cancer.

Comparison of two alternative sequences with cabazitaxel and 177Lu-PSMA-617 in metastatic castration-resistant prostate cancer: A retrospective multicenter study (LuCaS).

Perceived cognitive impairment and occupational functioning in prostate cancer survivors: an exploratory cross-sectional analysis.

Hematospermia does not increase the risk of prostate cancer detection in prostate biopsy.

Racial Differences in Survival and Healthcare Resource Utilization Among Medicaid-Insured Adults With Metastatic Prostate Cancer.

Impact of Endorectal Coil Use on Extraprostatic Extension Detection in Prostate MRI: A Retrospective Monocentric Study.

The interaction of structured data using openEHR and large Language models for clinical decision support in prostate cancer.

Activity of Platinum Chemotherapy in Men With Prostate Cancer With and Without DNA Damage Repair Mutations.

Cost-Effectiveness of PARP Inhibitors for Patients with BRCA1/2-Positive Metastatic Castration-Resistant Prostate Cancer-The Canadian Perspective.

Elderly Prostate Cancer Patients Treated with Robotic Surgery Are More Likely to Harbor Adverse Pathology Features and Experience Disease Progression: Analysis of the Prognostic Impact of Adverse Pathology Risk Score Patterns Using Briganti's 2012 Nomogra

Advanced Restriction Imaging and Reconstruction Technology for Prostate Magnetic Resonance Imaging (ART-Pro): A Study Protocol for a Multicenter, Multinational Trial Evaluating Biparametric Magnetic Resonance Imaging and Advanced, Quantitative Diffusion M

Staging of prostate Cancer with ultra-fast PSMA-PET scans enhanced by AI.

The Emerging Predictive and Prognostic Role of Aggressive-Variant-Associated Tumor Suppressor Genes Across Prostate Cancer Stages.

Evaluating the impact of the Radiomics Quality Score: a systematic review and meta-analysis.

Surgical Technique and Perioperative Outcomes of the "Sapienza" Urology Residency Program's Trocar Placement Configuration During Robotic-Assisted Radical Prostatectomy (RARP): A Retrospective, Single-Centre Observational Study Comparing Experienced Atten

Cost-utility analysis of MR imaging-guided transurethral ultrasound ablation for the treatment of low- to intermediate-risk localised prostate cancer.

An Overview of Patient-reported Outcomes for Men with Prostate Cancer: Results from the PIONEER Consortium.

Robot-Assisted PSMA-Radioguided Salvage Surgery for Oligorecurrent Prostate Cancer Using the Novel SENSEI® Drop-in Gamma Probe: Correlation of Intraoperative Measurements to Preoperative Imaging and Final Histology.

Lutetium-177 PSMA radioligand therapy in taxan-naive first- and second-line metastatic castration resistant prostate cancer after first-line ARPI therapy.

Cardiovascular Risk in Prostate Cancer: JACC: CardioOncology State-of-the-Art Review.

Clinical, Diagnostic and Therapeutic Framework of mHSPC and nmCRPC: A Multidisciplinary Consensus Project of the Italian Society for Uro-Oncology (SIUrO).

Androgen Receptor Pathway Inhibitor Therapy for Advanced Prostate Cancer: Secondary Analysis of a Randomized Clinical Trial.

Current Status of Neoadjuvant Treatment Before Surgery in High-Risk Localized Prostate Cancer.

eHealth, digital information and technology use of men with prostate cancer.

Comparison of Posttherapy 4- and 24-Hour [177Lu]Lu-PSMA SPECT/CT and Pretherapy PSMA PET/CT in Assessment of Disease in Men with Metastatic Castration-Resistant Prostate Cancer - Beyond the Abstract

Single Cell and Spatial Transcriptomics Highlight the Interaction of Club-like Cells with Immunosuppressive Myeloid Cells in Prostate Cancer - Beyond the Abstract

A Novel Machine Learning-Based Predictive Model of Clinically Significant Prostate Cancer and Online Risk Calculator - Beyond the Abstract

[225Ac]Ac-PSMA for the Treatment of Metastatic Castration-Resistant Prostate Cancer: A Systematic Review and Meta-Analysis - Beyond the Abstract

Identifying The Best Candidate for Focal Therapy: A Comprehensive Review - Beyond the Abstract

Increased Translation Driven by Non-Canonical EZH2 Creates a Synthetic Vulnerability in Enzalutamide-Resistant Prostate Cancer - Beyond the Abstract

Anatomic Factors Associated with Complications after Radical Prostatectomy: A Systematic Review and Meta-analysis - Beyond the Abstract

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