Rethinking Stone-free Rates and Surgical Outcomes in Endourology: A Point of View from PEARLS Members.

There is a lack of consensus on definitions for the success of endourological stone treatments. The zero-fragment rate (residual fragments [RFs] <1 mm) is now considered more accurate than the stone-free rate (RFs ≤4 mm). As stone volume may be adopted as the recommended method for preoperative estimation of the stone burden, the volumetric stone-free rate may be superior to standard linear RF measurements in defining success.

European urology. 2024 Jun 17 [Epub ahead of print]

Frédéric Panthier, Vineet Gauhar, Eugenio Ventimiglia, Jia-Lun Kwok, Etienne Xavier Keller, Olivier Traxer

Sorbonne University GRC Urolithiasis no. 20, Tenon Hospital, Paris, France; Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France; PIMM, UMR 8006 CNRS-Arts et Métiers ParisTech, Paris, France; Department of Urology, Westmoreland Street Hospital, UCLH NHS Foundation Trust, London, UK. Electronic address: ., Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France; Department of Urology, Ng Teng Fong General Hospital, Singapore., Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France; Young Academic Urologists Endourology and Urolithiasis Working Group, Arnhem, The Netherlands; Division of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy., Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France; Department of Urology, Tan Tock Seng Hospital, Singapore., Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France; Young Academic Urologists Endourology and Urolithiasis Working Group, Arnhem, The Netherlands; Department of Urology, University Hospital Zurich, University of Zurich, Zurich, Switzerland., Sorbonne University GRC Urolithiasis no. 20, Tenon Hospital, Paris, France; Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France; PIMM, UMR 8006 CNRS-Arts et Métiers ParisTech, Paris, France.