METHODS: The Rochester Epidemiologic Project was used to identify all Olmsted County, Minnesota residents diagnosed with urolithiasis from 1985 to 2008. New-onset DM was identified by diagnostic codes and treatment with SWL by surgical codes. Cox proportional hazards models were used to determine the risk of DM after SWL therapy.
RESULTS: A total of 5287 incident cases of stone formation without pre-existing DM and with ≥3 months of follow-up. After an average follow-up of 8.7 years, 423 patients (8%) were treated with SWL and new-onset DM had developed in 743 (12%). The diagnosis of DM followed SWL in 77 patients. However, no association was evident between SWL and the development of DM before (hazard ratio 0.98, 95% confidence interval 0.76-1.26) or after (hazard ratio 0.92, 95% confidence interval 0.71-1.18) SWL, controlling for age, sex, and obesity.
CONCLUSION: In the present large, population-based cohort, the long-term risk of developing DM was not increased in persons who underwent SWL to treat their kidney stones.
Written by:
Cógáin MD, Krambeck AE, Rule AD, Li X, Bergstralh EJ, Gettman MT, Lieske JC. Are you the author?
Department of Urology, Mayo Clinic College of Medicine, Rochester, Minnesota.
Reference: Urology. 2011 Nov 15. Epub ahead of print.
doi: 10.1016/j.urology.2011.07.1430
PubMed Abstract
PMID: 22088569
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