This study aimed to compare the safety and efficacy of treatment using simple prostatectomy (SP) and using photoselective vaporization of the prostate (PVP) with a 180W GreenLight XPS laser in patients with high-volume prostate hypertrophy.
The study included 120 patients with LUTS symptoms caused by prostatic enlargement of more than 80 ml; 79 patients were treated with SP, while 41 were treated with PVP. The analysis included subjective the International Prostate Symptom Score (IPSS) and Quality of Life (QoL), and objective (Qmax), (Qave), and post-void residual volume (PVR) parameters before treatment and at an average of 38 months after surgical treatment. Early and late adverse effects and length of hospitalisation were assessed. Complication reports were performed according to the modified Clavien-Dindo system.
The analysis independently showed the effectiveness of both methods. Subjective parameters (IPSS, QoL), showed no significant differences. Patients treated with SP scored slightly better on objective parameters (Qmax, Qave, and PVR). Analysis of adverse effects and hospitalisation time were more favourable after PVP.
SP and PVP were found to be comparable and highly effective in treating benign prostatic hyperplasia in terms of IPSS and QoL. Patients treated with the SP method obtained slightly better results of objective parameters such as Qmax, Qave, and PVR. Compared with SP, PVP has a more favourable safety profile.
Central European journal of urology. 2024 Jan 13 [Epub]
Hubert Burdziak, Tomasz Syryło, Agnieszka Grabińska, Karol Burdziak, Janusz Ławiński, Monika Tomaka, Henryk Zieliński
Department of Urology and Oncological Urology, Regional Hospital. St. Padre Pio in Przemysl, Przemyśl, Poland., Department of Urology, Oncological and Functional Urology, Military Institute of Medicine in Warsaw, Warsaw, Poland., Department of Urology and Oncological Urology, Medical University F. Chopin in Rzeszów, Poland., Department of Cardiology, University Hospital, Wroclaw, Poland.