Men with overactive bladder (OAB) and benign prostatic hyperplasia (BPH), will have deterioration in the quality of life.
The aim of this study was to evaluate the effect of combining pelvic floor muscle training with the urgency suppression technique (PFMT-st) and silodosin in comparison with silodosin in men with benign prostatic hyperplasia (BPH) and overactive bladder (OAB) after 12 weeks of treatment.
A total of 158 patients were randomized into two groups. The control group received oral silodosin at a daily dose of 8 mg. The experimental group was administered PFMT-st and silodosin. The evaluation methods included the number of voids and intensity of urgencies over 24 h using a micturition diary, the International Prostate Symptom Score (IPSS), the Overactive Bladder Questionnaire (OAB-q), and the patient global impression of improvement (PGI-I).
142 of 172 (86.6%) men were assessed (70 in the control group, 72 in the experimental group). The significant changes were in favor of the experimental group (p < 0.001) in the number of voids per 24 h (- 1.95 ± 1.94 vs. - 0.90 ± 1.44), the OAB-q symptom score (- 14.25 ± 10.05 vs. - 9.28 ± 10.60), the intensity of urgencies (- 0.97 ± 0.53 vs. 0.24 ± 0.57), the IPSS (- 4.59 ± 3.00 vs. - 2.30 ± 3.63), and in the PGI-I (2.24 ± 0.79 vs. 3.60 ± 0.92).
The addition of PFMT-st to silodosin treatment significantly improved OAB in men with BPH. This is the first study to confirm that PFMT-st should be the first-choice treatment for OAB in BPH.
World journal of urology. 2024 May 02*** epublish ***
Magdalena Hagovska, Jan Svihra, Ladislav Macko, Jan Breza, Jan Svihra, Jan Luptak, Lubomir Lachvac
Department of Physiatry, Balneology, and Medical Rehabilitation, Institution-Faculty of Medicine, PJ Safarik University, Kosice, Slovak Republic., Department of Urology, Jessenius Faculty of Medicine, Comenius University Bratislava, Martin, Slovak Republic. ., Outpatient Clinic of Urology, Urocentrum, Levice, Slovak Republic., Department of Pediatric Urology, Faculty of Medicine, Comenius University Bratislava, National Institute of Pediatric Diseases, Bratislava, Slovak Republic., Department of Urology, Jessenius Faculty of Medicine, Comenius University Bratislava, Martin, Slovak Republic., Department of Urology, Faculty of Medicine, PJ Safarik University, Kosice, Slovak Republic.