UroLift to preserve seminal parameters in young male with LUTS from BPH.

Prostatic urethral lift has been an effective ejaculation sparing treatment for benign prostatic hypertrophy. The aim of this study was to evaluate the effect on male semen parameters.

Between July 2014 and January 2022, 20 young men with urinary symptoms of BPH, unresponsive to drug treatment and motivated to preserve ejaculation for eventual paternity, underwent UroLift.

Semen analysis was performed before and 6 month after surgery with evaluation of pH, volume, sperm concentration, total motility, vitality and morphology according to WHO 2011. All underwent digital rectal examination, transrectal prostate ultrasound to measure prostate volume, PSA, uroflowmetry, cystoscopy and urodynamics test if necessary. Objective and subjective urinary function was scheduled at 1, 3, 6, 12 month than yearly with UFM, IPSS, IIEF-5, and MSHQ-EjD-SF.

At a mean follow-up of 36 month (range 12 to 63), no retroejaculation or changes in seminal parameters occurred. Mean age was 44.5 (range 36.5 to 48) years. Mean operative time was 15 (range 10 to 20) min and 2.5 (range 2 to 4) implants per patients were used. At 6 month there were no difference in terms of total sperm count, volume, pH, motility, vitality, morphology, liquefaction, leucocytes (p = 0.9; p = 0.8; p = 0.7; p = 1; p = 1; p = 1; p = 0,2; p = 0.5). At last, Q-max increased by 64.4% (p = 0.001), post-void residual volume decreased by 66.6% (p = 0.016), and IPSS decreased by 60% (p < 0.001). IIEF and MSHQ-EjD-SF were preserved (p = 0.14, p = 0.4).

UroLift appears safe technique to correct LUTS from BPH in young men desirous to preserve seminal analysis.

World journal of urology. 2024 Aug 16*** epublish ***

Pasquale Annese, Nicola d'Altilia, Ugo Giovanni Falagario, Edoardo Tocci, Vincenzo Mirone, Giuseppe Simone, Angelo Porreca, Carlo Bettocchi, Francesca Sanguedolce, Gian Maria Busetto, Giuseppe Carrieri

Department of Urology, IRCCS Ospedale Casa Sollievo Della Sofferenza, San Giovanni Rotondo, Italy., Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71122, Foggia, Italy. ., Department of Urology and Renal Transplantation, University of Foggia, Viale Luigi Pinto 1, 71122, Foggia, Italy., Department of Public Health, University of Naples "Federico II", Naples, Italy., Department of Urology, Regina Elena National Cancer Institute, Roma, Italy., Oncological Urology, Veneto Institute of Oncology (IOV)-IRCCS, Padova, Italy., Pathology Unit, University of Foggia, Foggia, Italy.

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