Prostatic urethral lift (PUL) for benign prostatic hyperplasia has recently been initiated in Asia; therefore, few studies with real-world data have been reported. This study evaluated the efficacy and safety of PUL using Japanese real-world multicenter data.
Indications for PUL were based on relevant guidelines in Japan. The preoperative patient status, postoperative progress at 1 and 3 months, and perioperative complications were evaluated. Also, we compared preoperative urinary retention and nonurinary retention patients, and prostate volumes <30, 30 to <50, and ≥50 mL.
A total of 160 patients were included in the study. The mean age was 75 years and the mean prostate volume was 44 mL. The International Prostate Symptom Score, quality of life score, maximum flow rate, and postvoid residual volume significantly improved 1 and 3 months postoperatively compared to preoperatively. The catheter-free rates in the preoperative urinary retention group were 58.1%, 72.1%, 83.7%, and 88.4% on postoperative days 1, 7, 30, and 90, respectively. The catheter-free rates in the nonurinary retention group were 94.9%, 98.3%, and 100% on postoperative days 1, 7, and 14, respectively. The group with a prostate volume ≥50 mL had a longer operation time and used significantly more implants; however, no difference was observed in the postoperative urinary status among the three groups.
PUL can be considered a safe and effective procedure for both preoperative urinary retention and nonurinary retention patients with prostate volumes <100 mL in older patients with comorbidities.
International journal of urology : official journal of the Japanese Urological Association. 2024 Nov 05 [Epub ahead of print]
Go Anan, Hidero Minami, Yosuke Fujishima, Kanya Kaga
Department of Urology, Yotsuya Medical Cube, Chiyoda City, Tokyo, Japan., Department of Urology, Tsurugi Hospital, Hakusan, Ishikawa, Japan., Department of Urology, Iwate Prefectural Iwai Hospital, Ichinoseki, Iwate, Japan., Department of Urology, Chiba Prefectural Sawara Hospital, Katori, Chiba, Japan.