BACKGROUND:To evaluate the efficacy and safety of GreenLight HPS(™) (High Performance System) laser photoselective vaporization prostatectomy (PVP) for the treatment of benign prostatic hyperplasia (BPH) in patients of different age groups.
METHODS:164 consecutive patients were stratified into two groups: age < 70 (group I, n = 93) and age ≥70 (group II, n = 71) years. Transurethral PVP was performed using a GreenLight HPS™ side-firing laser system. Voiding parameters were measured preoperatively and at 1 and 4 weeks and 3, 6, 12, 18, 24 and 36 months postoperatively.
RESULTS:Among the preoperative parameters evaluated, there were significant differences (p < 0.05) in prostate volume (I: 58.7; II: 73.6 mL) and serum prostate-specific antigen (I: 1.9; II: 2.9 ng/mL), while American Urological Association Symptom Score (AUASS), Quality of Life (QoL), maximum flow rate (Qmax), Sexual Health Inventory for Men (SHIM) and post void residual (PVR) were similar (p > 0.05) between groups. No significant differences in laser utilization, energy usage and operating time were noted. Clinical outcomes (AUASS, QoL, Qmax, PVR) showed immediate and stable improvement from baseline (p < 0.05) within each group, but no significant differences between the two groups were observed during the follow-up period. The incidence of adverse events was low and similar in both groups.
CONCLUSIONS: The results suggest that age has little effect on the efficacy and safety of GreenLight HPS™ laser PVP.
Written by:
Gu X, Strom K, Spaliviero M, Wong C. Are you the author?
Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Reference: Aging Male. 2012 Mar;15(1):63-7.
doi: 10.3109/13685538.2011.632452
PubMed Abstract
PMID: 22129103