Prostatic stromal hyperplasia with atypia (PSHA) is a rare histologic finding diagnosed incidentally on prostate biopsies, transurethral resection specimens, and radical prostatectomy specimens.
PSHA has a bizarre histologic appearance and these lesions often raise concern for sarcoma; however, their clinical course is indolent and does not include extraprostatic progression. We discuss a case of PHSA discovered on prostate biopsy performed for an abnormal digital rectal examination and review the literature on this rare pathologic finding.
Written by:
Hutchinson RC, Wu KJ, Cheville JC, Thiel DD. Are you the author?
Department of Urology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Reference: Case Rep Urol. 2013;2013:364124.
doi: 10.1155/2013/364124
PubMed Abstract
PMID: 23781384