Phosphodiesterase type 5 (PDE5) inhibitors are the most classic first-line medicine for male erectile dysfunction.
Recent researches have demonstrated that PDE5 inhibitors can also be employed in the treatment of lower urinary tract symptoms, renal ischemia/reperfusion injury and testicular torsion. This article updates the application of PDE5 inhibitors in these fields and their relevant mechanisms.
Written by:
Li Z, Lu H. Are you the author?
Department of Urology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Human Sperm Bank, Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai 200135, China.
Reference: Zhonghua Nan Ke Xue. 2013 Aug;19(8):675-7.
PubMed Abstract
PMID: 24010198
Article in Chinese.
