Benign prostate hyperplasia (BPH) is a common condition affecting older men, with an incidence that is age-dependent.
Histological BPH, which typically develops after the age of 40 years, ranges in prevalence from >50% at 60 years to as high as 90% by 85 years of age. Typical symptoms include increased frequency of urination, nocturia, urgency, hesitancy, and weak urine stream. Conventional medicines used for the treatment of BPH include alpha blockers and 5-alpha reductase inhibitors. This articles review the mode of action, the efficacy, and the safety, including herb-drug interactions of the most common botanicals (Serenoa repens, Pygeum africanum, Urtica dioica, and Cucurbita pepo) and nutraceuticals (isoflavones, lycopene, selenium, and β-Sitosterol) in controlling the lower urinary tract symptoms associated to BPH.
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Pagano E, Laudato M, Griffo M, Capasso R. Are you the author?
Reference: Phytother Res. 2014 Jul;28(7):949-55.
PubMed Abstract
PMID: 25165780