BACKGROUND: The aim of the study was to evaluate patients attitudes with benign prostatic hyperplasia at the risk of progression during a 12-month period of observation.
MATERIALS AND METHODS: A total of 426 patients from 45 outpatients centers were included and prospectively followed. Inclusion criteria were: age > 50 years, International Prostate Symptom Score (IPSS) > 8, prostate volume > 30 cm3 (transabdominal ultrasound) and PSA > 1.5 to < 10 ng/ml.
RESULTS: In all, 28.6 % patients were naive, 62.9 % used monotherapy (alpha-blocker), and 8.5 % combined treatment (alpha-blocker/5alpha-reductase inhibitor/dutasteride). The most bothersome symptoms were the weak urine stream (60.8 %) and nocturia (59.2 %). Patients expectations from the treatment were stabilization of the disease and reducing the risk of surgery rather than rapid resolution of symptoms. Despite the presence of symptoms, 2.3 % patients claimed that benign prostatic hyperplasia/lower urinary tract symptoms had no impact on their quality of life (QoL), in 48.1 % only little impact on QoL, and 47.9 % patients percepted their symptoms as severe. Out of 71.4 % patients treated previously, 26.5 % patients were indecisive about the satisfaction of present treatment. Visual analog score was percepted more optimistically rather than the IPSS. Pearson's correlation r = 0.68 at the beginning and r = 0.83 at the end of the study.
CONCLUSIONS: Prostate and Expectations of Treatment Epidemiology Research study highlights and reflects on patients behavior and self-perception, patients self-perception of the disease and therapeutic priorities during the 1 year of observation.
Written by:
Weibl P, Klatte T, Laurinc P, Tomaškin R, Shariat SF, Helbich M, Fackovcova D, Bujdák P. Are you the author?
Department of Urology, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Reference: Wien Klin Wochenschr. 2014 Dec 2. Epub ahead of print.
doi: 10.1007/s00508-014-0668-4
PubMed Abstract
PMID: 25447967