Defining the risks associated with diabetes mellitus in patients undergoing penile prosthesis implantation remains controversial. Our study aims to assess whether preoperative hemoglobin a1c and preoperative blood glucose levels are associated with an increased risk for postoperative infection in diabetic men. We performed a retrospective review of 932 diabetic patients undergoing primary penile prosthesis implantation from 18 high-volume penile prosthesis implantation surgeons throughout the United States, Germany, Belgium, and South Korea. Preoperative hemoglobin a1c and blood glucose levels within 6 h of surgery were collected and assessed in univariate and multivariate models for correlation with postoperative infection, revision, and explantation rates. The primary outcome is postoperative infection and the secondary outcomes are postoperative revision and explantation. In all, 875 patients were included in the final analysis. There were no associations between preoperative blood glucose levels or hemoglobin a1c levels and postoperative infection rates; p = 0.220 and p = 0.598, respectively. On multivariate analysis, a history of diabetes-related complications was a significant predictor of higher revision rates (p = 0.034), but was nonsignificant for infection or explantation rates. We conclude preoperative blood glucose levels and hemoglobin a1c levels are not associated with an increased risk for postoperative infection, revision, or explantation in diabetic men undergoing penile prosthesis implantation.
International journal of impotence research. 2020 Mar 20 [Epub ahead of print]
Mohamad M Osman, Linda M Huynh, Farouk M El-Khatib, Maxwell Towe, Huang-Wei Su, Robert Andrianne, Gregory Barton, Gregory Broderick, Arthur L Burnett, Jeffrey D Campbell, Jonathan Clavell-Hernandez, Jessica Connor, Martin Gross, Ross Guillum, Amy I Guise, Georgios Hatzichristodoulou, Gerard D Henry, Tung-Chin Hsieh, Lawrence C Jenkins, Christopher Koprowski, Kook B Lee, Aaron Lentz, Ricardo M Munarriz, Daniar Osmonov, Shu Pan, Kevin Parikh, Sung Hun Park, Amir S Patel, Paul Perito, Hossein Sadeghi-Nejad, Maxime Sempels, Jay Simhan, Run Wang, Faysal A Yafi
Department of Urology, Irvine Medical Center, University of California, Orange, CA, USA., Service d'urologie, Centre Hospitalier Universitaire de Liège, Liège, Belgium., Division of Urology, Duke University Medical Center, Durham, NC, USA., Department of Urology, Mayo Clinic, Jacksonville, FL, USA., The Johns Hopkins Hospital, Baltimore, MD, USA., University of Texas, MD Anderson Cancer Center, Houston, TX, USA., Department of Urology, Hackensack University Medical Center, Hackensack, NJ, USA., Section of Urology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA., Department of Urology, Medical College of Wisconsin, Milwaukee, WI, USA., Department of Urology, Julius-Maximilians-University of Würzburg, Würzburg, Germany., ArkLaTex Urology, Bossier City, LA, USA., Department of Urology, UC San Diego Health System, San Diego, CA, USA., Department of Urology, The Ohio State University, Columbus, OH, USA., Sewum Prosthetic Urology Center of Excellence, Seoul, South Korea., Department of Urology, Boston University Medical Center, Boston, MA, USA., Department of Urology, University Hospital Schleswig Holstein, Campus Kiel, Germany., Department of Urology, Fox Chase Cancer Center, Einstein Healthcare Network, Philadelphia, PA, USA., Perito Urology, Coral Gables, FL, USA., Department of Urology, Irvine Medical Center, University of California, Orange, CA, USA. .