We aimed to investigate the effect of continuous positive airway pressure (CPAP) administered for the treatment of obstructive upper airway on lower urinary tract symptoms and erectile dysfunction in male patients.
A total of 626 male with suspected obstructive sleep apnea syndrome (OSAS) were evaluated prospectively. Nocturnal polysomnography tests were administered to the male. After application of the exclusion criteria, 54 patients with severe OSAS (Apnea-Hypopnea Index ≥30) were included in the study. International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF-15), and nocturia were assessed in all patients before and after CPAP therapy, and prostate volume, total prostate-specific antigen (tPSA), and uroflowmetric measurements were assessed in patients aged >40 years.
The mean age of the 54 patients was 47.06±11.15 years. Post-treatment IIEF scores were better than pre-treatment scores (24.27±7.58 vs. 22.68±8.65, p=0.014). IPSS values, nocturia, and uroflowmetric outcomes significantly improved after CPAP therapy (p<0.05). On the other hand, mean values of body mass index, tPSA, prostate volume, and postvoid residual urine volume did not differ significantly after treatment.
CPAP therapy improves lower urinary tract symptoms, nocturia, and erectile dysfunction in male with severe OSAS.
Investigative and clinical urology. 2020 Sep 24 [Epub ahead of print]
Soner Coban, Aygul Gunes, Abdullah Gul, Ali Riza Turkoglu, Muhammet Guzelsoy, Murat Ozturk, Osman Akyuz, Ozgur Ekici
Department of Urology, University of Health Sciences, Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey. ., Department of Neurology, University of Health Sciences, Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey., Department of Urology, University of Health Sciences, Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey., Deparment of Urology, Medicine Hospital Biruni University, İstanbul, Turkey.