Inflatable penile prosthesis (IPP) is a surgical treatment for erectile dysfunction refractory to medical therapy or for those who desire permanent treatment. Complications like mechanical failure and infection may necessitate reoperation, and patients with certain risk factors remain predisposed to reoperation. We retrospectively analyzed 530 patients undergoing primary IPP implantation at a large, urban, multiethnic hospital with a high volume of IPP implantations. Primary outcomes were reoperation due to any reason and reoperation due to infection. Patient characteristics and intraoperative factors were compared between those requiring reoperation and those not requiring reoperation. Overall, 12.1% of patients underwent reoperation, primarily due to infection, with a median time to reoperation of 4 months. Analysis revealed an increased likelihood of reoperation with Peyronie's disease (OR = 2.47), hemoglobin A1c over 8 (OR = 2.25), active smoking (OR = 2.75), and estimated blood loss (EBL) ≥ 25cc (OR = 2.45). A decreased likelihood of reoperation was observed when Arista™ powder was used intraoperatively (OR = 0.38). Reoperation specifically due to infection was associated with an infrapubic approach (OR = 2.56) and hypertension (OR = 9.12). Our findings confirm smoking and diabetes as risk factors for reoperation, while also providing insights into factors like estimated blood loss and Arista™ powder use. However, long-term survival rates were limited by loss to follow-up. (Clinical trial registration N/A).
International journal of impotence research. 2024 Aug 26 [Epub ahead of print]
Noah Hawks-Ladds, Mustufa Babar, Kevin Labagnara, Justin Loloi, Rutul D Patel, Arshia Aalami Harandi, Michael Zhu, Azizou Salami, Pedro Maria
Albert Einstein College of Medicine, Bronx, NY, USA. ., Albert Einstein College of Medicine, Bronx, NY, USA., Department of Internal Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Long Island, NY, USA., Department of Urology, Montefiore Medical Center, Bronx, NY, USA., Department of Urology, Stony Brook University Hospital, Stony Brook, NY, USA.