INTRODUCTION: Intracavernosal injection (ICI) therapy is a well-recognized treatment strategy with high success rates for men with erectile dysfunction.
Despite this, injection anxiety and pain related to injection are significant barriers to its use.
AIMS: This study aims to examine injection anxiety and injection pain in patients using ICI.
METHODS: Men starting ICI therapy post radical pelvic surgery completed questionnaires at initial visit, at each of the two ICI training sessions and at a 4-month follow-up visit.
MAIN OUTCOME MEASURES: Injection Anxiety Scale, Injection Pain Scale, Injection Reaction Inventory, and the Erectile Function Domain of the International Index of Erectile Function.
RESULTS: Average age of the 68 men was 60 ± 8 years. At 4 months, the self-reported frequency of ICI use was: 29% < 1/week, 26% 1/week, 40% 2/week, and 5% 3/week. Mean injection anxiety score at first injection was 5.7 ± 2.8 (range 0-10) and significantly decreased to a 4.1 ± 3 at 4 months (P < 0.001). At first injection, 65% reported high injection anxiety (≥5) and this significantly decreased to 42% (P = 0.003) at 4 months. Anxiety at first injection was negatively related to ICI frequency at 4 months (r = -0.23, P = 0.08). Mean injection pain score at first injection was low (2.2 ± 1.8, range 0-10) and 59% rated injection pain ≤ 2. Injection pain remained consistent across time periods. At first injection, injection anxiety (assessed prior to injection) was related to injection pain (r = 0.21, P = 0.04) and subjects (n = 21) who reported high injection anxiety (≥5) across time points, reported an increase in injection pain scores from first injection to 4 months (2.7 vs. 3.7, P = 0.05).
CONCLUSIONS: Although injection anxiety decreased with ICI use, mean injection anxiety remained at a moderate level (4.4) and 42% of men continued to report "high" injection anxiety at 4 months. While injection pain was low, injection anxiety and pain were related. These data suggest the need for a psychological intervention to help lower injection anxiety related to ICI.
Written by:
Nelson CJ, Hsiao W, Balk E, Narus J, Tal R, Bennett NE, Mulhall JP. Are you the author?
Department of Psychiatry and Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Reference: J Sex Med. 2013 Jul 30. Epub ahead of print.
doi: 10.1111/jsm.12271
PubMed Abstract
PMID: 23898886
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