OBJECTIVE: To evaluate the results of nocturnal penile erection test and response to daily sildenafil in patients with erectile dysfunction (ED) due to pelvic fracture urethral disruption.
METHODS: From January 2010 to January 2012, we included 38 patients with ED due to pelvic fracture urethral disruption. The mean age was 33.1 years (range, 22-49 years). All were evaluated subjectively and objectively by the International Index of Erectile Function-5, nocturnal penile tumescence and rigidity (NPTR) test, and penile Doppler ultrasonography. Patients received daily sildenafil 50 mg for 3 months.
RESULTS: Thirty-one patients were followed up: 54.8% showed response to sildenafil defined as reporting successful vaginal penetration and intercourse. Patients with neurogenic, arterial, and venous EDs did not differ in efficiency rates (P = .587). However, the penile erectile rigidity recorded by NPTR test affected efficiency significantly (P = .046). Patients with tip rigidity >40% had the highest response rate (76.9%), but the response rate for patients with tip rigidity < 20% was only 22.2%.
CONCLUSION: NPTR recording can reveal resident erectile function in patients with ED due to trauma and is significant for selecting pharmacologic treatment as optimal therapy.
Written by:
Peng J, Zhang Z, Cui W, Yuan Y, Gao B, Song W, Xin Z. Are you the author?
Andrology Center, Peking University First Hospital, Beijing, China.
Reference: Urology. 2014 Oct 9. pii: S0090-4295(14)00903-0.
doi: 10.1016/j.urology.2014.08.006
PubMed Abstract
PMID: 25306478