Review study.
Alternative treatments to oral phosphodiesterase type 5 inhibitors (PDE5Is) in individuals with spinal cord lesions (SCLs) and erectile dysfunction (ED).
Italy.
Research clinical trials (1999-2014).
Twelve studies were selected. One article documented that 76% of subjects reached satisfactory sexual intercourse (SI) using intracavernosal injection of vasoactive medications (papaverine and prostaglandin E1). One study regarding perineal training showed a significant increase (P
Data are scant on the efficacy of ED treatments for SCL subjects who did not respond to PDE5Is. Further research should investigate the effects of any SCL treatments even when they are not strictly used for neurogenic sexual dysfunction. Spinal Cord advance online publication, 21 July 2015; doi:10. 1038/sc. 2015. 116.
Spinal cord. 2015 Jul 21 [Epub ahead of print]
G Lombardi, S Musco, J J Wyndaele, G D Popolo
Neuro-Urology Department, Careggi University Hospital, Florence, Italy. , Neuro-Urology Department, Careggi University Hospital, Florence, Italy. , Department of Urology, Antwerp University Hospital and University of Antwerp, Faculty of Medicine, Antwerp, Belgium. , Neuro-Urology Department, Careggi University Hospital, Florence, Italy.