Ejaculatory dysfunctions other than premature ejaculation are commonly encountered in specialized clinics; however, their characterization in community-dwelling men is lacking.
The aim of this study was to evaluate the prevalence, severity, and associated distress of four ejaculatory dysfunctions: delayed ejaculation (DE), anejaculation (AE), perceived ejaculate volume reduction (PEVR) and/or decreased force of ejaculation (DFE) as a function of demographic and clinical characteristics in men.
Observational analysis of 988 subjects presenting with one or more types of ejaculatory dysfunctions other than premature ejaculation who screened for a randomized clinical trial assessing the efficacy of testosterone replacement on ejaculatory dysfunction. Demographic and clinical characteristics were assessed as potential risk factors using regression analysis.
The main outcome measures used were ejaculatory dysfunction prevalence and scores (3-item Men's Sexual Health Questionnaire Ejaculatory Dysfunction-Short Form [MSHQ-EjD-SF]), and bother (MSHQ-EjD-SF Bother item) and sexual satisfaction/enjoyment (International Index of Erectile Function Questionnaire Q7, Q8) as a function of subject's age, race, body mass index (BMI) and serum testosterone levels (measured by liquid chromatography tandem mass spectrometry).
Mean (standard deviation [SD]) age of the participants was 52 years (11). Eighty-eight percent of the men experienced more than one type of ejaculatory dysfunction and 68% considered their symptoms to be bothersome. Prevalence of the ejaculatory dysfunctions was substantial across a range of age, race, BMI, and serum testosterone categories. Prevalence of PEVR and DFE were positively associated with age (
The majority of the participants experienced multiple ejaculatory dysfunctions and found them to be highly bothersome. Ejaculatory dysfunctions were prevalent across a wide range of demographic and clinical characteristics. Paduch DA, Polzer P, Morgentaler A, Althof S, Donatucci C, Ni X, Patel AB, and Basaria S. Clinical and Demographic Correlates of Ejaculatory Dysfunctions Other Than Premature Ejaculation: a Prospective, Observational Study. J Sex Med **;**:**-**.
The journal of sexual medicine. 2015 Oct 29 [Epub ahead of print]
Darius A Paduch, Paula Polzer, Abraham Morgentaler, Stanley Althof, Craig Donatucci, Xiao Ni, Ankur B Patel, Shezhad Basaria
Department of Urology, Weill Cornell Medical College, New York, USA. , Eli Lilly and Co. , Indianapolis, USA. , Men's Health Boston, Chestnut Hill, USA. , Center for Marital and Sexual Health of South Florida, West Palm Beach, USA. , Eli Lilly and Co. , Indianapolis, USA. , Eli Lilly and Co. , Indianapolis, USA. , Eli Lilly and Co. , Indianapolis, USA. , Brigham and Women's Hospital, Harvard Medical School, Section on Men's Health, Aging and Metabolism, Boston, USA.