Long-term success durability of transurethral resection of ejaculatory duct in treating infertile men with ejaculatory duct obstruction.

The current study aimed to evaluate the long-term outcomes of TURED (transurethral resection of the ejaculatory duct) in treating male infertility due to ejaculatory duct obstruction (EDO) to the short-term follow-up.

From 2000 to 2010, we retrospectively reviewed 30 men with infertility resulting from EDO who underwent TURED. Information on preoperative evaluation of patients was collected from the medical records. Standardized semen analysis was performed six weeks, three months, and 12-months postoperatively, as well as after a seven-years follow-up. Telephone and mail were used for the long-term follow-up.

The average age of patients was 35.5±2.6. All patients had low ejaculate volume and normal rang of the mean serum hormone levels (gonadotropins and testosterone). Transrectal ultrasonography (TRUS) assessment, revealed midline cysts in 46.7% (n=14 cases), a seminal vesicle dilatation in 83.3% (25/30 cases) and ED dilatation in 76.7% (23/30 patients). In addition, two patients (6.6 %) underwent magnetic resonance images (MRI) pelvis to confirm equivocal EDO by TRUS. After short-term and long-term follow-up, semen parameters improved significantly in 90% of cases versus 63.3% of cases, respectively, with statistically insignificant differences in all parameters (p ≥ 0. 1). Based on subgroup analysis, semen parameters improved in all partial EDO and cystic EDO cases versus complete EDO and non-cystic EDO, respectively. Spontaneous pregnancies were achieved in 10 (33.3 %) versus 8 (26.6 %) cases after short and long term, respectively. Regarding post-TURED complications, we reported 23.3 % (n=7).

TURED is an effective treatment for ejaculatory duct obstruction. It significantly improves all semen parameters and improves the symptoms related to EDO after short and long-term follow-up.

Journal of endourology. 2022 Feb 14 [Epub ahead of print]

Ibrahim Abdel-Al, Adel Elatreisy, Ahmed Mohey, Gamal M Hassan, Tarek Gharib

Al-Azhar Faculty of Medicine for Men in Asyut, 486470, Urology, Assiut, Assiut, Egypt, 71511; ., Al-Azhar University Faculty of Medicine, 68821, urology, Cairo, Egypt; ., Benha University Faculty of Medicine, 68817, Urology , Benha, Egypt; ., Al-Azhar Faculty of Medicine for Men in Asyut, 486470, urology, Assiut, Asyut, Egypt; ., Benha University Faculty of Medicine, 68817, Urology, Benha, Egypt; .