Polyorchidism is an uncommon congenital condition often discovered incidentally, which may significantly impact male fertility. We present a case of a 34-year-old man with unilateral polyorchidism and associated severe asthenozoospermia and teratozoospermia. Despite normal hormonal levels and no detected genetic anomalies, the patient's sperm showed mitochondrial damage, and his fertility remained compromised after conservative management and assisted reproductive attempts. This case underscores the intricate relationship between polyorchidism and male infertility, highlighting the need for personalized management strategies and further research into its etiology and impact.
BMC urology. 2024 Oct 18*** epublish ***
Fang Yang, Jingyi Zhang, Yao Xiao, Shiyun Pu, Meijing Wang, Shengxi Xiong, Xinyi Tang, Xujun Yu, Degui Chang
TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, No.37, Twelve Bridges Road, Jinniu District, Chengdu City, Sichuan Province, 610075, China., Chengdu Fifth People's Hospital, The Second Clinical Medical College, Affiliated Fifth People's Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610041, China., TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, No.37, Twelve Bridges Road, Jinniu District, Chengdu City, Sichuan Province, 610075, China. ., TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, No.37, Twelve Bridges Road, Jinniu District, Chengdu City, Sichuan Province, 610075, China. .