Reversible testosterone-induced azoospermia in a 45-year-old man attending an infertility outpatient clinic - Abstract

Andrology Centre, Reproductive Unit, Department of Obstetrics and Gynecology, University Medical Centre Ljubljana, Ljubljana, Slovenia.

Department of Endocrinology, Diabetes and Metabolic Diseases, University Medical Centre Ljubljana, Ljubljana, Slovenia.

 

 

A 45-year-old male with azoospermia was presented to us with primary infertility. We found that he had been taking testosterone due to erectile dysfunction. Upon its discontinuation, the normozoospermia was restored. This led to a pregnancy. In men aged 40-50, the diagnostic work up of testosterone deficiency should be in accordance with the current guidelines. Moreover, no testosterone prescription should be made without having inquired about parenthood desires. In men of the reproductive age with recent-onset azoospermia, consider the possibility of an iatrogenic cause, primarily due to the testosterone replacement therapy. The treatment is simple: to discontinue the therapy.

Written by:
Jan Z, Pfeifer M, Zorn B.   Are you the author?

Reference: Andrologia. 2011 Jul 18. Epub ahead of print.

PubMed Abstract
PMID: 21762190

UroToday.com Male Infertility and Reproduction Section