Diagnosis and treatment of azoospermia resulting from testicular sarcoidosis - Abstract

McMaster Institute of Urology, St. Joseph’s Hospital, 50 Charlton Avenue East, Hamilton, Ontario L8N 4A6, Canada.

 

Genitourinary sarcoidosis is uncommon with only rare documented cases of testicular involvement reported. We detail the case of a 37 year old male who initially presented for azoospermia and secondary infertility. A testicular biopsy revealed non-necrotizing granulomas and a chest X-Ray identified perihilar lymphadenopathy and granulomatous lung nodules. A corticosteroid regiment was administered and routine semen analyses were conducted. Significant improvements were noted following prednisone treatments. A successful, in-vivo fertilization was obtained. This is the first known case of testicular sarcoidosis diagnosed during investigations into azoospermia and secondary infertility which, following treatment with corticosteroids, resulted in a natural fertilization.

Written by:
Kovac JR, Flood D, Mullen JB, Fischer MA.   Are you the author?

Reference: J Androl. 2011 May 19. Epub ahead of print.

PubMed Abstract
PMID: 21546613

UroToday.com Male Infertility and Reproduction Section