Background: MAGI is an acronym that identifies the "male accessory gland inflammations/infections", a potential cause of male infertility.
Type 2 diabetes mellitus (DM2) prevalence is going to increase among men of reproductive age. Due to the high prevalence of these two conditions, we could suppose that they might appear together in the same patient.
Aim: To evaluate MAGI prevalence in patients with DM2 in fertile age.
Subjects and Methods: A cross-sectional study carried out on patients with DM2 of fertile age. All patients underwent andrological evaluation for the identification of conventional MAGI diagnostic criteria.
Results: DM2 patients showed a frequency of MAGI about 43%, significantly lower (p< 0.05) than in infertile patients of the same age without diabetes, which showed a MAGI overall frequency of 61%. Among examined diabetic patients the prevalence of MAGI did not significantly differ between patients attending for diabetes care problems (glycemic control) and patients with andrological disorders. Finally, no significant difference in seminal inflammatory signs frequency was detected between patients with DM2 and infertile patients without diabetes. Finally, the correlation analysis showed a significant direct correlation between duration of diabetes and glycemic control with the prevalence of MAGI.
Conclusion: MAGI prevalence in DM2 is lower than the one detected in age matched infertile non-diabetic patients, however, as in infertile patients, there is a high frequency of seminal inflammatory signs. Moreover, the observed prevalence among diabetic patients with diabetes care problems and diabetic patients with andrological problems is not statistically different.
Written by:
Condorelli RA, Calogero AE, Vicari E, Duca Y, Favilla V, Morgia G, Cimino S, Di Mauro M, La Vignera S. Are you the author?
Section of Endocrinology, Andrology and Internal Medicine, Department of Medical and Pediatric Sciences, University of Catania, Italy.
Reference: J Endocrinol Invest. 2013 Apr 30. Epub ahead of print.
PubMed Abstract
PMID: 23633651
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