OBJECTIVE: To determine and compare autonomic dysfunction in patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
METHODS: The subjects were 30-60 years old and had no known systemic disease. Electrocardiographic signals in the patients in the resting state were obtained from 59 patients with CP/CPPS (age 46.5 ± 7.02 years) and 94 healthy subjects (age 48.4 ± 5.96 years), and heart rate variability parameters were compared.
RESULTS: The standard deviation of the N-N interval (P < .001), square root of the mean squared differences of the successive N-N intervals (P = .004), total power (P = .004), very low frequency (P = .012), and high frequency (P < .001) were lower in the patients with CP/CPPS. However, no significant differences were found in the low frequency and low frequency/high frequency ratios.
CONCLUSION: Patients with CP/CPPS exhibited lower heart rate variability parameters compared with normal controls, with the exception of low frequency and low frequency/high frequency ratios. Possible differences in autonomic nervous system between those with CP/CPPS and normal healthy subjects could exist and autonomic dysfunction might be 1 of the causes that aggravates CP/CPPS.
Written by:
Cho DS, Choi JB, Kim YS, Joo KJ, Kim SH, Kim JC, Kim HW. Are you the author?
Department of Urology, Ajou University School of Medicine, Suwon, Korea.
Reference: Urology. 2011 Dec;78(6):1369-72.
doi: 10.1016/j.urology.2011.07.1379
PubMed Abstract
PMID: 21996103
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