UPOINT: A novel phenotypic classification system for chronic prostatitis/chronic pelvic pain syndrome - Abstract

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common condition obsessing urologists and patients.

It is also known as a heterogeneous syndrome, with varied etiologies, progression courses and responses to treatment. Based on the deeper insights into its pathogenesis and re-evaluation of its clinical trials, a novel phenotypic classification system UPOINT has been developed, which clinically classifies CP/CPPS patients into six domains: urinary (U), psychosocial (P), organ-specific (O), infection (I) , neurologic/systemic (N) and tenderness of pelvic floor skeletal muscles (T), and directs individualized and multimodal therapeutic approaches to CP/CPPS. This review systematically summarizes the theoretical foundation, clinical characteristics of UPOINT and treatment strategies based on the UPOINT phenotypic classification system.

Written by:
Liu LF, Wang L, Lu TF, Qi L, Zu XB.   Are you the author?
Department of Urology, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China.

Reference: Zhonghua Nan Ke Xue. 2012 May;18(5):441-5.


PubMed Abstract
PMID: 22741445

Article in Chinese.

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