INTRODUCTION: To evaluate the clinical phenotypes of patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using a web based online tool and to compare these clinical features with patients evaluated in a tertiary referral clinic.
MATERIALS AND METHODS: Data was collected from 720 men who gave complete online responses on a website which determines the UPOINT clinical phenotype in CP/CPPS and measures symptom severity with the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI). This was compared to phenotype and symptom severity of 220 patients evaluated in person at a tertiary referral clinic.
RESULTS: The web-based cohort had CPSI scores of 11.1, 4.8, 7.6, and 23.6 for pain, urinary, quality-of-life, and total score, respectively. The percentage of patients positive for each domain was 76%, 74%, 75%, 10%, 46%, and 75% for the urinary, psychosocial, organ specific, infection, neurologic/systemic, and tenderness domains, respectively. There was a positive correlation between CPSI and number of positive UPOINT domains (p = 0.25, p < 0.0001). Comparison between web- and clinic-based groups showed that the clinic group had fewer UPOINT positive domains compared to the web-based group (2.9 versus 3.6, p < 0.0001), but had worse quality-of-life (9.0 versus 7.6, p < 0.0001) and CPSI total scores (25.0 versus 23.6, p = 0.0052).
CONCLUSIONS: Men using an online tool to clinically phenotype CP/CPPS show similar correlations between UPOINT domains, symptom severity, age and duration. While symptom severity was worse in patients seen in a tertiary referral clinic, the differences were small.
Written by:
Tran CN, Li J, Shoskes DA. Are you the author?
The Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Reference: Can J Urol. 2014 Apr;21(2):7195-200.
PubMed Abstract
PMID: 24775571
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