Treatment options for prostatitis caused by multidrug-resistant gram-negative bacilli (MDR-GNB) are limited.
We report two cases cured with oral fosfomycin and provide a pharmacokinetic analysis of fosfomycin pre-dose concentrations during treatment. Oral fosfomycin 3 g once-daily for 12 to 16 weeks was a safe and effective treatment for MDR-GNB prostatitis.
Written by:
Grayson ML, Macesic N, Trevillyan J, Ellis AG, Zeglinski PT, Hewitt NH, Gardiner BJ, Frauman AG. Are you the author?
Department of Infectious Diseases, Austin Health, Melbourne, Australia; Department of Medicine, University of Melbourne, Melbourne, Australia; Department of Infectious Diseases, Alfred Health, Melbourne, Australia; Department of Clinical Pharmacology, Austin Health, Melbourne, Australia.
Reference: Clin Infect Dis. 2015 Jun 10. pii: civ436.
doi: 10.1093/cid/civ436
PubMed Abstract
PMID: 26063723