To examine the efficacy and safety of tadalafil in the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia with chronic pelvic pain syndrome, we treated 23 Japanese men with tadalafil 5 mg once daily for 4 weeks. The mean age of the participantswas58.7 yearsand the prostate volume was25. 2 ml. Significant improvementsin total International Prostatic Symptom Score, International Prostatic Symptom Score Quality of Life Index, total National Institutes of Health Chronic Prostatitis Symptom Index score, pain subscore, urinary symptom subscore, and quality of life impact subscore, were observed for tadalafil versus before treatment. These findings confirm that tadalafil is a valuable new treatment option for patients with benign prostatic hyperplasia complicated by chronic pelvic pain syndrome.
Hinyokika kiyo. Acta urologica Japonica. 2017 Mar [Epub]
Yoshinori Nishino, Kousei Miwa, Yoji Moriyama, Shigeru Fujihiro, Takako Masue, Mina Kikuchi, Chie Nakai, Takashi Deguchi
Nishino Clinic., The Department of Urology, Japanese Red Cross Gifu Hospital., The Department of Urology, Ogaki Municipal Hospital., The Department of Urology, Tokai Central Hospital., The Department of Urology, Division of Disease Control, Research Field of Medical Sciences, Graduate School of Medicine, Gifu University.