Neuroblastoma is an extracranial malignant tumor in children that is most often located in the adrenal gland and sympathetic ganglion. Here, we present a rare case of neuroblastoma originating from the urinary bladder.
A 3-year-old girl presented with lower abdominal pain with micturition. Ultrasound revealed a lower abdominal mass. Abdominal computed tomography scan displayed a solitary mass at the top of the urinary bladder. Blood levels of neuron-specific enolase and lactate dehydrogenase were elevated. We treated the child with partial cystectomy and six courses of chemotherapy, and the outcome at 4-year follow-up was unremarkable.
Neuroblastoma should be considered when tumors are located in the urinary bladder, especially in the dome; although this presentation is rare, the prognosis is very good.
World journal of clinical cases. 2020 Jan 06 [Epub]
Jia-Bin Cai, Jin-Hu Wang, Min He, Fa-Liang Wang, Jie-Ni Xiong, Jun-Qing Mao, Min-Ju Li, Kun Zhu, Jia-Wei Liang
Division of Surgical Oncology, Department of Pediatric Surgery, Children's Hospital, Zhejiang University School of Medicine; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China., Division of Surgical Oncology, Department of Pediatric Surgery, Children's Hospital, Zhejiang University School of Medicine; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China. ., Department of Pathology, Children's Hospital, Zhejiang University School of Medicine; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China., Department of Radiology, Children's Hospital, Zhejiang University School of Medicine, ; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China.