Urodynamic Center, Department of Urology of the First Affiliated Hospital of Zhengzhou University, Institute of Clinical Medicine of Zhengzhou University, Zhengzhou, China.
To summarize the clinical features and follow-up, the effects of melamine-tainted milk powder (MMP) consumption on kidney and body growth in children who suffered from melamine-related urinary stones (MUS) 2 years earlier were checked.
Body height and weight, kidney and bladder morphology monitored by ultrasound, urinalysis and renal function were recorded. Plain abdominal radiography was performed for differential diagnosis. The first follow-up was carried out at 15 months and the second 2 years later for patients who showed any abnormality at the first follow-up. Two hundred age- and gender-matched cohorts were included.
All cases received conservative treatment in hospital. Fifteen months of follow-up was successfully carried out in 167 cases. 91 children had residual MUS at the time of discharge, 58 MUS disappeared completely, 25 dissolved partially, 1 increased in size, and 7 did not change. At 2 years of follow-up, the residual stones all disappeared except for 1 case; the patient who showed a delayed development with regard to height caught up at 24 months of follow-up.
Conservative treatment shows a high effectiveness in cases with residual MUS. Consumption of MMP with timely treatment did not demonstrate an evident impact on kidney and bladder although body height is slightly affected in a few cases.
Written by:
Wen JG, Chang QL, Lou AF, Li ZZ, Lu S, Wang Y, Wang YL, Hu JH, Mao SP, Zhang Y, Xue R, Ren C, Xing L, Zhang GX, Zhang S, Djurhuus JC, Frøkiaer J. Are you the author?
Reference: Urol Int. 2011 Nov 1. Epub ahead of print.
doi: 10.1159/000330795
PubMed Abstract
PMID: 22057293
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