Despite several recent studies, the advisability of antimicrobial prophylaxis and certain imaging studies for urinary tract infections (UTIs) remains controversial.
The role of vesicoureteral reflux (VUR) on the severity and re-infection rates for UTIs is also difficult to assess. Registries and repositories of data and biomaterials from clinical studies in children with VUR are valuable. Disease registries are collections of secondary data related to patients with a specific diagnosis, condition or procedure. Registries differ from indices in that they contain more extensive data. A research repository is an entity that receives, stores, processes and/or disseminates specimens (or other materials) as needed. It encompasses the physical location as well as the full range of activities associated with its operation. It may also be referred to as a biorepository. This report provides information about some current registries and repositories that include data and samples from children with VUR. It also describes the heterogeneous nature of the subjects, as some registries and repositories include only data or samples from patients with primary reflux while others also include those from patients with syndromic or secondary reflux.
Written by:
Chesney RW, Patters AB. Are you the author?
Department of Pediatrics, Le Bonheur Children's Hospital, University of Tennessee Health Science Center, 50 N. Dunlap, Memphis, TN 38103, USA.
Reference: J Pediatr Urol. 2012 Oct 5. pii: S1477-5131(12)00226-4.
doi: 10.1016/j.jpurol.2012.09.003
PubMed Abstract
PMID: 23044377
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