Rhabdomyosarcomas are the most common soft tissue sarcomas in children.
Here we present management of an 18-month-old boy with metastatic rhabdomyosarcoma of the bladder/prostate. After radiochemotherapy, high-spatial-resolution 3-Tesla multiparametric magnetic resonance imaging (MRI) showed regressive systemic disease but a residual mass at the right seminal vesicle. For histologic re-evaluation, 3-dimensional-controlled stereotactic MRI/transrectal ultrasound (TRUS)-fusion biopsy specimens were taken. Because histologic analysis showed nonvital tissue, a decision could be made against adjuvant radical cystoprostatectomy. Advanced 3-Tesla imaging and MRI/TRUS-fusion biopsies in children are feasible and represent an effective tool to examine suspicious pelvic lesions. Depending on histology, this can lead to a significant reduction of therapy-associated morbidity.
Written by:
Kuru TH, Roethke MC, Nyarangi-Dix J, Okouoyo S, Stockklausner C, Schenk JP, Debus J, Roth W, Teber D, Pahernik S, Schlemmer HP, Hohenfellner M, Hadaschik BA. Are you the author?
Department of Urology, UniversityHospital Heidelberg, Heidelberg, Germany; Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Reference: Urology. 2013 Feb;81(2):417-20.
doi: 10.1016/j.urology.2012.10.043
PubMed Abstract
PMID: 23374821
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