Xanthogranulomatous pyelonephritis (XGP) is a chronic renal inflammatory lesion that is rarely diagnosed in children.
We present a case of a 16-year-old boy presenting with gross hematuria and a lack of laboratory and radiographic findings for XGP who was suspected of having renal cell carcinoma on urine cytology. Left radical nephrectomy was performed, confirming the diagnosis of XGP. The cytologic mimicking of renal cell carcinoma by XGP emphasizes that physicians should consider XGP in the differential diagnosis. The inability of urine cytopathology to distinguish XGP from renal cell carcinoma suggests a need for the development of new pathology techniques.
Written by:
Inouye BM, Chiang G, Newbury RO, Holmes N. Are you the author?
State University of New York at Stony Brook School of Medicine, Brooklyn, NY; Division of Pediatric Urology, Rady Children's Hospital, San Diego, CA.
Reference: Urology. 2013 Apr;81(4):885-7.
doi: 10.1016/j.urology.2012.12.019
PubMed Abstract
PMID: 23394878
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