We report 4 patients with upper urinary tract (UUT) obstruction requiring ureteric reimplantation at 1, 7, 28, and 63 months after dextranomer/hyaluronic acid copolymer (Dx/HA) injection for vesicoureteric reflux.
Histopathologic evaluation of ureteric segments revealed extensive foreign body formation in all cases. We conclude that UUT obstruction is a rare but serious complication after Dx/HA injection that can occur even years after surgery. The incidence of delayed-onset UUT obstruction may be higher than previously noted. Long-term follow-up and a critical reappraisal of the method are needed to assess the late sequelae of Dx/HA injection therapy for vesicoureteric reflux.
Written by:
Rubenwolf PC, Ebert AK, Ruemmele P, Rösch WH. Are you the author?
Department of Pediatric Urology, University Medical Centre Regensburg, Clinic St. Hedwig, Regenburg, Germany.
Reference: Urology. 2013 Mar;81(3):659-62.
doi: 10.1016/j.urology.2012.11.044
PubMed Abstract
PMID: 23452811
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