Voiding dysfunction is a common entity in pediatric urology.
It is believed to have a multifactorial etiology. The aim of this study was to investigate whether there is an increased prevalence of generalized joint hypermobility (GJH) in children with voiding dysfunction compared to normal children. Moreover, the prevalence of voiding complaints in patients with and without GJH was assessed. A total of 226 children-aged 5 to 14 years-including 113 patients diagnosed with voiding dysfunction and 113 sex/age/body mass index-matched normal children were recruited. GJH was evaluated in both groups using the Beighton score (4 or more = hypermobile). In the patient's group, GJH was significantly more frequent than in controls: 51/113 (45 %) versus 19/113 (17 %) (P = 0.001). In addition, in both groups, GJH was more prominent in girls than boys (P < 0.05). Urinary tract infection was the most frequent features in children with voiding dysfunction (64 %). In the subgroup of positive GJH, urinary tract infection remained the most common manifestation among the girls (P = 0.003), while constipation was the most prevalent manifestation among the boys (P = 0.001). Conclusion: Our findings suggest that children with voiding dysfunction have significantly higher prevalence of GJH compared to normal children. Further studies are needed to determine the cause and effect of these two common presentations and will help to develop a multidisciplinary approach in understanding and management of voiding dysfunction in children.
Written by:
Kajbafzadeh AM, Sharifi-Rad L, Ladi Seyedian SS, Mozafarpour S, Paydary K. Are you the author?
Pediatric Urology Research Center and Department of Pediatric Urology, Children's Hospital Medical Center, Pediatric Center Excellence, Tehran University of Medical Sciences, Qarib's St, Keshavarz Blvd, Tehran, 14194 33151, Iran.
Reference: Eur J Pediatr. 2013 Aug 20. Epub ahead of print.
doi: 10.1007/s00431-013-2120-6
PubMed Abstract
PMID: 23959325
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